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Mutational Analysis of Driver and Non-driver Mutations of Philadelphia Chromosome-negative Myeloproliferative Neoplasms; Diagnosis and Recent Advances in Treatment

World Journal of Cancer and Oncology Research | Vol 3, Issue 1

Figure 1

Structural domains of <i>JAK2 </i>showing Exon 14. FERM, Ezrin, Radixin, Moesin subdomains; JH1 and JH2, JAK Homology 1 and 2 domains; SH2 indicates Src Homology 2 domain. Amino acid positions are indicated with numbers: blue indicates V617F mutation.
Figure 1. Structural domains of JAK2 showing Exon 14. FERM, Ezrin, Radixin, Moesin subdomains; JH1 and JH2, JAK Homology 1 and 2 domains; SH2 indicates Src Homology 2 domain. Amino acid positions are indicated with numbers: blue indicates V617F mutation.
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