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Pallidum Functional Hypoconnectivity and Inhibitory Control as Partial Mediators of Environmental Influences on Tobacco and Marijuana Initiation

Journal of Cellular Neuroscience | Vol 1, Issue 1

Table 1. Summary of structural equation modeling (SEM)

Predictor OutcomeBSE95%CI
Age→PM2.50.0000.009-0.0180.0180.984
Male→PM2.5-0.0140.009-0.0320.0050.140
Parental education→PM2.5-0.1000.011-0.121-0.079< 0.001
Asian→PM2.50.0510.0090.0330.069< 0.001
Married household→PM2.5-0.0390.011-0.059-0.018< 0.001
Other→PM2.50.0980.0100.0790.117< 0.001
Latino→PM2.50.0990.0110.0780.120< 0.001
Black→PM2.50.1960.0110.1750.218< 0.001
PM2.5→rsFC between the right pallidum and ventral attention network-0.0250.010-0.045-0.0060.012
Age→rsFC between the right pallidum and ventral attention network0.0200.0040.0120.029< 0.001
Male→rsFC between the right pallidum and ventral attention network-0.0230.010-0.042-0.0040.018
Parental education→rsFC between the right pallidum and ventral attention network-0.0170.010-0.0370.0030.097
Married household→rsFC between the right pallidum and ventral attention network0.0000.011-0.0200.0210.978
rsFC between the right pallidum and ventral attention network→Low Inhibitory Control0.1120.0110.0910.134< 0.001
rsFC between the right pallidum and ventral attention network→Substance Use Initiation-0.0240.012-0.0480.0000.050
Low Inhibitory Control→Substance Use Initiation-0.0570.027-0.111-0.0040.037
Age→Substance Use Initiation0.0490.0040.0410.056< 0.001
Male→Substance Use Initiation-0.0130.012-0.0350.0100.265
Parental education→Substance Use Initiation-0.0880.011-0.110-0.066< 0.001