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Optimization of Delirium Care in Adult Patients with Cancer: A Comprehensive and Integrative Review of Efficacy and Patient Outcomes
World Journal of Clinical Medicine Research
| Vol 4, Issue 1
Table 5. Synthesis of Studies on Deliriumin Patients with Advanced Cancer
| Theme | Subtheme | Study | Findings |
| Prevalence of Delirium in Advanced Cancer Patients | Delirium prevalence in palliative care for advanced cancer | Mercadante et al. (2018) [41] | - 17.5% of advanced cancer patients experienced delirium during palliative care - Delirium decreased to 10.3% after one week of intervention |
| Chishi et al. (2023) [10] | - Delirium prevalence rate of 24.1% - Improvement observed after palliative intervention | ||
| Maeda et al. (2020) [39] | - 22.1% of advanced cancer patients experienced delirium during palliative care | ||
| Prevalence of delirium in diverse palliative care settings | De La Cruz et al. (2015) [11] | - A 10.3% delirium prevalence rate among cancer patients admitted to an acute palliative care unit- A 30.5% delirium incidence rate in patients admitted to an acute palliative care unit | |
| Chishi et al. (2023) [10] | - A 62% delirium prevalence rate among patients admitted to a hospice center - Reduced to 24.1% with treatment | ||
| Mercadante et al. (2018) [41] | - 11.5% delirium prevalence rate among advanced cancer patients in home care and hospice | ||
| Management and Treatment of Delirium in Advanced Cancer Patients | Efficacy of pharmacological interventions in the management of delirium in advanced cancer | Agar et al. (2017) [1] | - Risperidone and haloperidol are more effective than placebo in reducing delirium symptoms - No significant difference between the two antipsychotics in terms of efficacy or safety |
| Okuyama et al. (2019) [45] | - Current pharmacotherapy did not improve the severity of hypoactive delirium in patients with advanced cancer | ||
| Maeda et al. (2020) [39] | - Antipsychotic medication for delirium was effective and safe in real-world palliative care settings | ||
| Efficacy of non-pharmacological approach in management of delirium in advanced cancer | Tatematsu et al. (2011) [48] | - Exercise therapy effective in reducing delirium in cancer patients | |
| Mercadante et al. (2018) [41] | - Palliative care associated with a reduction in the incidence and severity of delirium | ||
| Matsuda et al. (2020) [40] | - Multicomponent interventions involving non-pharmacological approaches were effective- Environmental modifications reduced the severity and duration of delirium | ||
| Chishi et al. (2023) [10] | - Addressing the physical, emotional, and spiritual needs of the patient showed positive impacts- Incorporating palliative care interventions may be effective in managing delirium | ||
| Reversibility of Delirium in Hospitalised Cancer Patients | Mercadante et al. (2018) [41], Chishi et al. (2023) [10], Matsuda et al. (2021) [40], | - Delirium in hospitalized cancer patients generally reversible- Improvements observed with palliative care interventions, antipsychotic medications, and exercise therapy | |
| Matsuda et al. (2021) [40], | - Delirium reversibility rate may vary depending on the underlying etiology- Identifying and managing underlying etiologies crucial in improving delirium outcomes | ||
| Okuyama et al. (2019) [45], | - Pharmacotherapy for managing delirium symptoms may have limited efficacy in hypoactive delirium subtype | ||
| Agar et al. (2017) [1] | - Risperidone and haloperidol effective in managing delirium symptoms in palliative care patients |